K. Sreekumaran Nair, M.D., an endocrinologist at Mayo Clinic, Rochester, Minn., who has studied DHEA supplements,Â talks about DHEA.Â Â
What Is DHEA?
The manufacture of DHEA starts in the pituitary axis, which releases ACTH (adrenocorticotrophic hormone). ACTH signals the adrenal glands to manufacture DHEA from cholesterol. It is released into the bloodstream as DHEAS (DHEA sulfate). Dubbed the “mother of all steroids,” DHEA is the most abundant steroid in the human body and is involved in the manufacture of testosterone, estrogen, progesterone, and corticosterone. The decline of DHEA with age parallels that of HGH, so that by age sixty-five, your body makes only 10 to 20 percent what it did at age twenty.
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