Jul

30

Tens of thousands of boys (and some girls) in this country receive injections of human growth hoemone (HGH), the pituitary secretion pivotal to the complex hormonal cascade that mediates height.

The story of growth hormone contains many of the most painful object lessons of modern health care. First it was painstakingly harvested from cadavers, and the tiny supply was reserved for children with pituitary failure. But as we know now, human tissues make perilous drugs, and the recipients of cadaver hormone grew up under the hanging sword of the neurological condition Creutzfeldt-Jakob disease, transmitted by some of those shots.

Then, in 1985, new technology flooded the marketplace with synthetic human growth hormone (HGH), safe from infectious contaminants and made in quantities enough to treat not just the truly pituitary-deficient, but all small-comers.

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Jul

15

Here is an unbelieveable story out of Ireland: 

 Parents for Justice says it wants an investigation into hospitals’ previous practice of selling human pituitary glands to drugs companies.

The campaign group wants the inquiry to look into payments from drugs firms to hospitals for supplying the gland from deceased children without the consent of families.

Today, the organisation published documents it has obtained under the Freedom of Information Act, detailing payments by two drugs companies to hospitals during the 1970s and 1980s.

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Mar

27

 Randy Wakefield knows firsthand about the benefits AND the dangers of HGH:

As a child, Wakefield, now 42, was diagnosed as a hypopituitary dwarf and given human growth hormone (HGH) injections to help him grow. At that time, during the 1960s and 1970s, HGH was naturally derived — that is, it was made by processing pituitary glands taken from cadavers.

Wakefield and the others grew taller, but in 1985 the experiment was found to have a fatal flaw. Three HGH recipients contracted a rare neurological illness called Creutzfeldt-Jakob disease (CJD), otherwise known as the human equivalent of “mad cow” disease.

Wakefield has so far dodged the CJD bullet, but he has been plagued with myriad health problems, including chronic depression and obesity.

His life began turning around last September, when Wakefield began receiving daily injections of an unlikely new treatment, which helped him lose approximately 60 pounds and find the energy to go out and look for a job. The treatment? A new, synthetic version of human growth hormone (HGH).

Wakefield thus finds himself in the peculiar position of taking the synthetic version of the very thing that has caused him so much grief.

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Feb

6

HGH Trial Opens

February 6, 2008 | Leave a Comment

 Years ago, HGH used to be harvested from human cadaver pituitary glands. The result was catastrophic in many cases. Take a look:

Seven doctors and pharmacists went on trial Wednesday for the deaths of more than 100 young people who died of a brain-destroying disease after being treated with tainted HGH.

Hundreds of family members packed the courtroom where the defendants faced charges, including manslaughter and deception, following a 17-year investigation into the deaths of at least 110 young people from Creutzfeldt-Jakob disease, or CJD.

From the 1960s through the 1980s, HGH collected from the pituitary glands of human corpses were used to treat thousands of French children whose growth was stunted because of a deficiency in the secretion of growth hormone.

The program ended in 1988 after contaminated growth hormones were linked to CJD — three years after the United States and Britain stopped the practice because patients had contracted the fatal brain disease.

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Trial Opens In HGH Deaths

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