Sep

25

The biopharmaceutical market, estimated to be about $40 billion annually, is one of the fastest-growing segments of the life sciences industry.

When pharmaceutical giants Sandoz (Novartis),  launched Omnitrope, its biosimilar version of human growth hormone (HGH) in Germany two years ago, the price was discounted 20% as compared with Eli Lilly’s Humatrope brand. Also, in Australia biosimilar versions of HGH are sold at a 25% discount as compared with their branded counterparts.

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Aug

5

Israel’s Teva (pronounced teh-vuh) is the world’s biggest generic-drug maker. By making knockoffs faster and in bigger quantities than the competition, the company now accounts for 22% of all generic prescriptions written in the U.S.

Competitors have come out swinging. Swiss drug giant Novartis (NVS) recently won the rights to sell a biogeneric version of Pfizer’s Genotropin, a human growth hormone (HGH), in Japan, and Merck (MRK, Fortune 500) announced plans to develop biogenerics through a division called BioVentures. “Teva is going to be competing with the big boys,” says Sanford Bernstein analyst Ronny Gal.

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May

13

(PhysOrg.com) — A new method developed by Cornell biological engineers offers an efficient way to make proteins for use in medicine or industry without the use of live cells. The proteins made in this way include many that cannot be produced by current biotechnology.

Current methods employ vats of genetically modified bacteria or mammalian cells that churn out proteins for such pharmaceuticals as insulin or human growth hormone (hgh). But there are many proteins that bacteria or cells cannot tolerate. Anti-microbials, for example, are meant to kill bacteria and so would kill the host. And many key proteins that are important in regulating the normal life of a cell would also kill the host if overproduced inside a cell.

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Apr

1

The history of biotechnology dates back to at least 5,000 years when the first loaf of bread was baked from fermented dough, the first alcoholic drink was brewed and the first pots of cheese and yoghurt were made. The modern era of biotechnology began in 1868 with the discovery of DNA by the German scientist, F Meischer.

DNA carries the hereditary information that determines the structure of proteins which are the essential structural and functional components of cells. Much of the transforming power of biotechnology relies on enzymes, which are catalytic proteins. DNA also controls things like cell division, differentiation and whether it will live or die, remain normal or become cancerous.

Biotechnology is broadly defined as a multi-disciplinary field which utilises a myriad of techniques and approaches to exploit biological systems for a variety of commercial and industrial purposes. The scientific and conceptual foundations of biotechnology are derived from molecular biology, genetics, biochemistry, microbiology and chemical and process engineering. Some well-known biotechnology products are insulin, interferon, human growth hormone (hgh), somatostatin and antibiotics. The list also includes recombinant vaccines and commercially available diagnostic and research kits.

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