Dec

31

An Orlando pharmacy whose operators were snared nearly three years ago in an Albany County criminal probe has been implicated in an international network that federal authorities say smuggled human growth hormone from China to the United States, court records show.

The controversial drug is strictly regulated by the U.S. Food and Drug Administration. Yet human growth hormone, or HGH, has been used by professional athletes, bodybuilders, celebrities and others who subscribe to its anti-aging and muscle rejuvenating effects.

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Dec

31

A single 30-minute and three 10-minute bouts of physical activity increased 24-hour integrated serum growth hormone concentrations in young adults.

These data suggest that both continuous and intermittent exercise may be beneficial in promoting increases in 24-hour GH secretion in obese and nonobese individuals, according to researchers at the University of Virginia and Mayo Clinic in Rochester.

“We originally hypothesized that three 10-minute bouts of exercise would result in a greater 24-hour GH release than the single 30-minute bout of exercise. It may be that just 10 minutes of exercise at a time is not enough to create an additive response because the total response was the same as with a single 30-minute bout of exercise,” said Arthur Weltman, PhD, director of the Exercise Physiology Program at the University of Virginia.

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Dec

29

Alzheimer’s & HGH

December 29, 2009 | Leave a Comment

Researchers at the Salk Institute for Biological Studies in San Diego have made one of the biggest breakthroughs in anti-aging and Alzheimer’s research in the last 40 years: They’ve discovered a way to use hormone pathways to slow the aging process in the brains of mice, and they hope the technique could lead to the development of drugs both to prevent and treat Alzheimer’s disease in humans.

The scientists at the Salk Institute focused on IGF-1 (insulin-like growth factor 1), which has been called the fountain of youth hormone and has been found to extend life expectancy in humans, worms, and mice. IGF-1 functions as a mediator for human growth hormone (HGH), which plays a critical role in the aging process. HGH promotes tissue repair and cell regeneration in the bones, supports the immune system in combating infection and disease, and ensures that as cells die off, healthy replacements are on hand. In other words, HGH is a factory of health and vitality. But as we age, our HGH level declines, and old cells cannot be replaced as readily with new ones. The body’s ability to self-repair is impaired. This is called aging.

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Dec

27

The breakdown in negotiations between boxing champions Manny Pacquiao and Floyd Mayweather, Jr. over Pacquiao’s apparent resistance to submit to an Olympic-style blood test has presented MMA with a golden opportunity to further differentiate itself from the often frustrating sport of boxing.

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UFC President Dana White never misses an opportunity to point out his frustrations with boxing, being a former boxing manager himself.  He touts how his management of the UFC has transcended boxing’s chaotic system which often leads to disappointing match-ups, padded records, and confusing rankings. But, performance enhancing drugs is an area where boxing beats MMA, at least in numbers of fighters who test positive in a urinalysis given by state athletic commissions.  Most concerning is the number of fighters at the top of the sport who’ve tested positive, including UFC Hall of Famers Royce Gracie (14-3-3) and “The World’s Most Dangerous Man” Ken Shamrock (26-12-2).Gracie tested positive after defeating “Gracie Hunter” Kazushi Sakuraba (22-13-1) at K-1 HERO’s Dynamite!! USA in June 2007 and Shamrock tested positive after defeating Ross Clifton (6-10) at War Gods in February 2009. And, at this point I’d like to emphasize that both Gracie and Shamrock deny using performance enhancing drugs.  In fact, I’d like to make a blanket statement that nearly every fighter who tests positive denies use. The UFC even presented a lightweight title fight between Fighters.com’s ninth-ranked lightweight “Muscle Shark” Sean Sherk (33-4-1) and Hermes Franca (18-6) at UFC 73 in July 2007 after which both fighters tested positive.  (Franca actually admits using banned substances.) The UFC is just the most prominent and active promotion; and, to White’s credit, under his leadership the UFC has worked with U.S. states not sanctioning MMA to put in place mandates on testing and the UFC implements its own tests when promoting events not within a sanctioning framework that mandates tests. MMA’s problem with performance enhancing substances extends outside of the UFC.  The biggest heavyweight fight of 2009 between Fighters.com Champion “Last Emperor” Fedor Emelianenko (31-1) and eighth-ranked “Babyface Assassin” Josh Barnett (20-5) at Affliction Trilogy in August was cancelled when Barnett tested positive for banned substances before the fight.  It was the former UFC champion’s second positive test during his career. Now, think of all the boxing champions who’ve failed a urinalysis.  Coming up a bit short? I’m not naive.  Perhaps boxers are just more adept at techniques that obscure their use from a urinalysis; and, a blood test is beatable too. But, a blood test administered by the World Anti-Doping Agency or a subsidiary, like the United States Anti-Doping Agency that Mayweather is requiring before he’ll fight Pacquiao, is the best contemporary sport has to detect banned substances. And, blood tests can determine use of human growth hormone (HGH) in particular, which Mayweather is suspicious of Pacquiao using.

Dec

22

While human growth hormone (HGH) has a remarkable ability to generate controversy, exactly what it does for athletes, both good and bad, is as much of a mystery today as when it first found favor as a performance booster during the 1990s.

“That’s uncharted territory,” said Richard J. Auchus, a professor of endocrinology at the University of Texas Southwestern Medical School in Dallas. “We just don’t know what happens when people use high doses for long periods of time.”

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Dec

21

Continuation of some form of drug therapy is the best way to prevent HIV from developing into AIDS. However, certain side effects may be severe enough to warrant discontinuation or alteration of medications.

Dietary changes, exercise and cholesterol-lowering medications may be used to counteract concerns of heart disease in patients taking protease inhibitors or nucleoside reverse transcriptase inhibitors. In people with prior elevated risks for heart disease, a physician may have other recommendations, such as the use of a different class of drugs. Symptoms of nausea, vomiting and diarrhea should be discussed with a physician. These could be signs of liver damage. In some cases, symptoms will subside or a physician may decide to change medication. Body fat redistribution can be treated in several ways. Dietary changes or certain medications such as Glucophage (metformin) may be ordered for those who have fat accumulation in their body. For those who appear to be losing fat, injections of human growth hormone (HGH) may be given.

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Dec

18

It looks like children with growth deficiencies will soon be able to get easy access to Pfizer’s human growth hormone Genotropin on the National Health Service after it won the National Institute for Health and Clinical Excellence’s favour.

The cost watchdog has published an appraisal consultation document in which it recommends the use of the drug to treat children with short stature due to: growth hormone deficiency; Turner syndrome; Prader–Willi syndrome; chronic renal insufficiency; being born small for gestational age; and short stature homeobox-containing gene (SHOX) deficiency.

While the Institute has ruled that the drug is indeed a cost-effective use of NHS resources, as there are seven preparations of somatropin available in the UK - including Eli Lilly’s Humatrope, Novo Nordisk’s Norditropin and Merck Serono’s Saizen - it has stressed that doctors must consider all the therapies and the likelihood of treatment adherence and then ultimately select the most suitable one with the lowest acquisition cost.

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Dec

17

Goji Berry & HGH

December 17, 2009 | Leave a Comment

Did you know that Goji berry is known as the “longevity fruit?”

Goji berries stimulates the secretion by the pituitary gland of HGH (human growth hormone), the youth hormone. The benefits of HGH includes; reduction of body fat, better sleep, improved memory, accelerated healing, restored libido and a more youthful appearance.

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Dec

15

A Canadian doctor who has treated many NFL players as well as Olympic medalists like Donovan Bailey and the world’s top golfer, Tiger Woods, is under criminal investigation in the United States. He is suspected of providing athletes with performance-enhancing drugs, according to several people who have been briefed on the investigation.

The F.B.I. investigation of Dr. Anthony Galea, a sports medicine specialist who has treated hundreds of professional athletes across many sports, follows his arrest on Oct. 15 in Toronto by the Canadian police. Human growth hormone and Actovegin, a drug extracted from calf’s blood, were found in his medical bag at the United States-Canada border in late September. Using, selling or importing Actovegin is illegal in the United States.

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Dec

10

Many competitive bodybuilders take anabolic steroids to achieve their freakishly exaggerated physiques. That is no secret. But steroids can be only one part of an extreme regimen that can wreak havoc on the body.

Human growth hormone (HGH), supplements, painkillers and diuretics can also be used to create the “shrink-wrapped” muscles so prized in the aesthetic. And the high concentration of muscle mass puts stress on the body, as if the lifter were obese.

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