Jun

23

Despite significant reduction in cholesterol levels in adults with growth hormone deficiency treated with recombinant human growth hormone (rhGH), taking lower doses of rhGH may not result in improvement in cardiac structure and function, according to research presented here at the Endocrine Society’s 91st Annual Meeting.

A recent meta-analysis showed that GH replacement improves exercise performance and has positive effects on cardiac structure, body composition, and lipids, said Katalin A. Frisch, MD, Department of Medicine, New York University Medical Center, New York, New York.

“Most studies included in the meta-analysis employed supraphysiological concentrations of GH, from 6 to 15.7 mg per week,” noted Dr. Frisch on June 11.

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